Originalarbeiten

• • Weber F, Canbay A: Attitudes of physicans and nursing stuff members toward organ donation in urban area of Germany. Transplant Proc 1999; 31: 2179-80. [IF 1,0]
  • Canbay A, Ella R, Weber F: Attitudes towards cadaveric organ donation: Comparison of German and Turkish citizens in Germany. Org Tiss 2001; 1:29-35. [IF 1,8]
  • Canbay A, Higuchi H, Bronk SF, Taniai M, Sebo TJ, Gores G: Fas enhances fibrogenesis in the bile duct ligated mouse: A link between apoptosis and fibrosis. Gastroenterology 2002; 122:1323-0. [IF 12,0]
  • Canbay A, Knorz S, Heimann K-D, Hildmann H, Tiedjen K-U: Wertigkeit der Szinti-graphie und der Sonographie in der Diagnostik der Zystadenolymphome der Glandula parotis. Laryngo-Rhino-Otology 2002;81:815-9. [IF 0,7]
  • Higuchi H, Bronk SF, Taniai M, Canbay A, Gores GJ: Cholestasis increases tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-R2/DR5 expression and sensitizes the liver to TRAIL-mediated cytotoxicity. J Pharmacol Exp Ther 2002;303:461-7. [IF 4,0]
  • Yoon JH, Werneburg NW, Higuchi H, Canbay A, Kaufmann SH, Akgul C, Edwards SW, Gores GJ: Bile acids inhibit Mcl-1 protein turnover via an epidermal growth factor receptor/Raf-1-dependent mechanism. Cancer Res 2002;62:6500-5. [IF 8,2]
  • Goebel MU, Trebst A, Steiner J, Xie YF, Exton MS, Frede S, Canbay A, Michel MC, Heemann U, Schedlowski M: Behaviorally conditioning is possible in man. FASEB J 2002;16:1869-3. [IF 6,5]
  • Canbay A, Tamir P, Torok N, Higuchi H, Friedman S, Gores GJ: Apoptotic body engulfment by human stellate cell line is profibrogenic. Lab Invest 2003; 83:655-3. [IF 4,4]
  • Canbay A, Guicciardi ME, Higuchi H, Feldstein AE, Bronk SF, Taniai M, Rydzewski R, Gores GJ: Cathepsin B inactivation attenuates hepatic injury and fibrosis during cholestasis. J. Clin. Invest. 2003;112:152-9. [IF 14,2]
  • Feldstein A, Canbay A, Angulo-Hernandez P, Taniai M, Burgart LJ, Lindor KD, Gores GJ. Hepatocyte apoptosis in patients with nonalcoholic steato-hepatitis: Quantification and clinical relevance. Gastroenterology. 2003;125: 437-443. [IF 12,0]
  • Canbay A, Feldstein AE, Higuchi H, Werneburg N, Grambihler A, Bronk SF, Gores GJ: Kupffer cell engulfment of apoptotic bodies stimulates death ligand and cytokine expression. Hepatology. 2003;38:1188-98. [IF 10,9]
  • Feldstein AE, Canbay A, Guicciardi ME, Higuchi H, Bronk SF, Gores GJ: Diet associated hepatic steatosis sensitizes to Fas mediated liver injury in mice. J Hepatol 2003;39:978-983. [IF 9,3]
  • Higuchi H, Grambihler A, Canbay A, BronkSF, Gores GJ: Bile acids upregulate death receptor 5/TRAIL-receptor 2 expression via a c-Jun N-terminal kinase-dependent pathway involving Sp1. J Biol Chem. 2004; 279: 51-60. [IF 5,3]
  • Yoon JH, Canbay A, Werneburg NW, Lee SP, Gores GJ: Oxysterols induce cyclooxygenase-2 expression in cholangiocytes: Implications for biliary tract carcinogenesis. Hepatology 2004; 39:732-738. [IF 10,9]
  • Canbay A, Feldstein AE, Baski-Bey E, Bronk SF, Gores GJ: The Caspase Inhibitor IDN-6556 Attenuates Hepatic Injury and Fibrosis in the Bile Duct Ligated Mouse. J Pharmacol Exp Ther 2004; 308:1191-1196. [IF 4,0]
  • Feldstein AE, Werneburg NW, Canbay A, Guicciardi ME, Bronk SF, Rydzewski R, Gores GJ: Free fatty acids promote hepatic lipotoxicity by stimulating TNF-alpha expression via a lysosomal pathway. Hepatology 2004;40:185-194. [IF 10,9]
  • Baumann M, Witzke O, Canbay A, Patschan S, Treichel U, Gerken G, Philipp T, Kribben A. Serum C3 complement concentrations correlate with liver function in patients with liver cirrhosis. Hepato-Gastroenterology. 2004;51(59):1451-3. [IF 0,7]
  • Baskin-Bey ES, Canbay A, Bronk SF, Werneburg N, Guicciardi ME, Nyberg SL, Gores GJ. Cathepsin B inactivation attenuates hepatocyte apoptosis and liver damage in steatotic livers after cold ischemia/warm reperfusion injury. Am J Physiol Gastrointest Liver Physiol. 2005;288:396-402. [IF 3,5]
  • Canbay A, Chen S-Y, Gieseler RK, Malago M, Karliova M, Broelsch CE, Gerken G, Treichel U. Overweight patients are more susceptible for acute liver failure. Hepato-Gastronterology 2005 Sep-Oct;52(65):1516-20. [IF 0,7]
  • Kip SN, Gray NW, Burette A, Canbay A, Weinberg RJ, Strehler EE. Changes in the Expression of plasma membrane calcium extrusion systems during the maturation of hippocampal neurons. Hippocampus. 2006;16:20-34. [IF 4,6]
  • Tillmann HL, Hadem J, Leifeld L, Zachou K, Canbay A, Eisenbach C, Graziadei I, Encke J, Schmidt H, Vogel W, Schneider A, Spengler U, Gerken G, Dalekos DN, Wedemeye H; Mann MP: Safety and efficacy of lamivudine in patients with severe acute or fulminant hepatitis B, a multicenter experience. J Viral Hepatitis. 2006; 4:256-63. [IF 3,5]
  • Saner FH, Olde Damink SW, Pavlakovic G, van den Broek MA, Rath PM, Sotiropoulos GC, Radtke A, Canbay A, Paul A, Nadalin S, Malagó M, Broelsch CE. Pulmonary and blood stream infections in adult living donor and cadaveric liver transplant patients. Transplantation. 2008 ;85:1564-8. [IF 3,7]
  • Bockhorn M, Fingas C.D, Rauen U, Canbay A, Frey U, Wohlschläger J, Sotiropoulos GC, Frilling A, Broelsch CE, Schlaak JF. Erythropoietin treatment improves liver regeneration in rat models of liver resection and living related liver transplantation via upregulation of c-jun and inhibition of apoptosis. Transplantation. 2008; 86:1578-1585. [IF 3,7]
  • Wedemeyer I, Bechmann L, Odenthal M, Jochum C, Marquitan G, Drebber U, Gerken G, Gieseler R, Dienes HP, Canbay A. Adiponectin Inhibits Steatotic CD95/Fas Upregulation by Hepatocytes: Therapeutic Implications for Hepatitis C. J Hepatol 2009 Jan;50(1):140-9. [IF 9,3]
  • Landgraeber S, Jaeckel S, Löer F, Wedemeyer C, Totsch M, Hilken G, Canbay A, von Knoch M. Pan-caspase inhibition supresses polyethylene particle-induced osteolysis. Apoptosis 2009;14(2):173-81. [IF 4,4)
  • Bechmann L, Zahn D, Gieseler RK, Fingas CD, Marquitan G, Jochum C, Gerken G, Friedman S, Canbay A. Resveratrol Amplifies Profibrogenic Effects of Free Fatty Acids on Human Hepatic Stellate Cells. Hepatol Res 2009; 39(6):601-8. [IF 1,9]
  • Canbay A, Jochum C, Bechmann L, Festag S, Yüksel Z, Saner F, Gerken G. Retrospective Study of Acute Liver Failure in Residents of a Metropolitan Area in Germany: Correlation of Cholestatic Enzymes and Body Mass Index with Clinical Outcome. Z Gastroenterol 2009;47(9):807-13 [IF 1,1]
  • Heuer M; Kaiser GM, Saner FH, Erim Y, Wirges U, Paul A, Gerken G, Canbay A. Eine konsequente Aufklärung könnte der türkisch-islamisch stämmigen Bevöl-kerung deutlich erhöhen. Med Welt 2009 04. [IF:0]
  • Saner FH, Heuer M, Meyer M, Canbay A, Sotiropoulos C, Radtke A, Treckmann J, Beckebaum S, Dohne-Schwake C, Oldedamink SW, Paul A. When the heart kills the liver: Acute liver failure in congestive heart failure. Eur J Med Res 2009, Dec 14;14(12):541-6 [IF 1,1]
  • Jochum C, Gieseler RK, Gawlista I, Fiedler A, Manka P, Saner FH, Roggendorf M, Gerken G, Canbay A. Hepatitis B-associated Acute Liver Failure: Immediate Treatment with Entecavir Inhibits HBV Replication and potentially its Sequelae. Digestion. 2009;80(4):235-40 [IF 2,1]
  • Tan S, Bechmann LP, Benson S, Dietz T, Eichner S, Hahn S, Janssen OE, Lahner H, Gerken G, Mann K, Canbay A. Apoptotic Markers Indicate Nonalcoholic Steatohepatitis in Polycystic Ovary Syndrome. J Clin Endocrinol Metab. 2010 Jan,95(1):343-8. [IF 6,5]
  • Landgraeber S, Wegner A, Canbay A, von Knoch M. Serum levels of adipo-nectin in patients with aseptic loosening after total hip replacement. J Biomed Mater Res A. 2010 May;93(2):748-52. [IF 3,0]
  • Fingas CD, Katsounas A. Nückel H. Kahraman A, Siffert W, Jochum C, Gerken G, Canbay A. Prognostic assessment of three single-nucleotide polymorphisms (GNB3 825C>T, BCL2 938C>A, MCL1 386C>G) in cholangiocarcinoma. Cancer Invest. 2010 Jun;28(5):472-8. [IF 2,4]
  • Kahraman A, Schlattjan M, Kocabayoglu P, Yildiz-Meziletoglu S, Schlensak M, Fingas CD, Wedemeyer I, Marquitan G, Gieseler R, Baba H, Gerken G. Canbay A. Major Histocompatibility Complex Class I-related Chains A and B (MIC A/B): A Novel Role in Non-Alcoholic Steatohepatitis. Hepatology. 2010;51(1):92-102 [IF 10,9]
  • Kahraman A, Hilsenbeck J, Nyga M, Ertle J, Wree A, Plauth M, Gerken G, Canbay AE. Bioelectrical impedance analysis in clinical practice: implications for hepatitis C therapy BIA and hepatitis C. Virol J. 2010 Aug 16;7:191. [IF 2,5]
  • Bechmann LP, Gieseler RK, Sowa JP, Kahraman A, Erhard J, Wedemeyer I, Emons B, Jochum C, Feldkamp T, Gerken G, Canbay A. Apoptosis is assoc-iated with CD36/fatty acid translocase upregulation in non-alcoholic steatohep-atitis. Liver Int 2010;30(6):850-859. [IF 3,8]
  • Dechêne A, Sowa JP, Gieseler RK, Jochum C, Bechmann LP, El Fouly A, Schlattjan M, Saner F, Baba HA, Paul A, Dries V, Odenthal M, Gerken G, Friedman SL, Canbay A. Acute liver failure is associated with elevated liver stiffness and hepatic stellate cell activation. Hepatology 2010;52(3):1008-1016. [IF 10,9]
  • Bechmann LP, Jochum C, Kocabayoglu P, Sowa JP, Kassalik M, Gieseler RK, Saner F, Paul A, Trautwein C, Gerken G, Canbay A. Cytokeratin 18-based modification of the MELD score improves prediction of spontaneous survival after acute liver injury. J Hepatol. 2010 Oct;53(4):639-647. [IF 9,3]
  • Thielmann M, Mechmet A, Neuhäuser M, Wendt D, Tossios P, Canbay A, Massoudy P, Jakob H. Risk prediction and outcomes in patients with liver cirrhosis undergoing open-heart surgery. Eur J Cardio-Thorac 2010;38(5):592-9.[IF 2,3]
  • Rey JW, Noetel A, Hardt A, Canbay A, Alakus H, Zur Hausen A, Dienes HP, Drebber U, Odenthal M. Pro12Ala polymorphism of the peroxisome proliferator-activated receptor γ2 in patients with fatty liver diseases. World J Gastroenterol. 2010 Dec 14;16(46):5830-7. [IF 2,2]
  • Gieseler RK, Marquitan G, Schlattjan M, Sowa JP, Bechmann LP, Timm J, Roggendorf M, Gerken G, Friedman SL, Canbay A. Hepatocyte apoptotic bodies encasing nonstructural HCV proteins amplify hepatic stellate cell activation: implications for chronic hepatitis C. J Viral Hepatitis. 2011; 18(11):760-7. [IF 3,5]
  • Ertle J, Dechêne A, Sowa JP, Penndorf V, Herzer K, Kaiser G, Schlaak JF, Gerken G, Syn WK, Canbay A. Nonalcoholic fatty liver disease progresses to HCC in the absence of apparent cirrhosis. Int J Cancer. 2011;128(10):2436. [IF 4,9]
  • Yoon MS, Obermann M, Dockweiler C, Assert R, Canbay A, Haag S, Gerken G, Diener HC, Katsarava Z. Sensory meuropathy in patients with cryoglobulin negative hepatitis-C infection. J Neurol. 2011 Jan;258(1):80-8. [IF 3,9]
  • Saner FH, Neumann T, Canbay A, Treckmann JW, Hartmann M, Goerlinger K, Bertram S, Beckebaum S, Cicinnati V, Paul A. High brain-natriuretic peptide level predicts cirrhotic cardiomyopathy in liver transplant patients. Transpl Int. 2011;24(5):425. [IF 3,2]
  • Jochum C, Beste M, Sowa JP, Farahani MS, Penndorf V, Nadalin S, Saner F, Canbay A, Gerken G. Glutathione-S-transferase subtypes α and π as a tool to predict and monitor graft failure or regeneration in a pilot study of living donor liver transplantation. Eur J Med Res. 2011 27;16(1):34-40. [IF 1,1]
  • Wree A, Dechêne A, Herzer K, Hilgard P, Syn WK, Gerken G, Canbay A. Steroid and Ursodesoxycholic Acid Combination Therapy in Severe Drug-Induced Liver Injury. Digestion. 2011 8;84(1):54-59. [IF 2,1]
  • Kälsch J, Bechmann LP, Kälsch H, Schlattjan M, Erhard J, Gerken G, Canbay A. Evaluation of Biomarkers of NAFLD in a Cohort of Morbidly Obese Patients. J Nutr Metab. 2011;2011:369168. [IF 0]
  • Herzer K, Kneiseler G, Bechmann LP, Post F, Schlattjan M, Sowa JP, Neumann T, Marggraf G, Erbel R, Gerken G, Canbay A, Jochum C. Onset of heart failure determines the hepatic cell death pattern. Ann Hepatol. 2011;10(2):174-9. [IF 1,9]
  • Seydel S, Beilfuss A, Kahraman A, Aksoy K, Gerken G, Akkiz H, Canbay A. Vitamin D ameliorates stress ligand expression elicited by free fatty acids in the hepatic stellate cell line LX-2. Turk J Gastroenterol. 2011;22(4):400-7. [IF 0,6]
  • Dechêne A, Bechmann LP, Windeck S, Gerken G, Canbay A, Zöpf T. Magnetic Endoscopic Imaging saves abdominal compression and patient pain in routine colonoscopies. J Digest Dis. 2011;12(5):364-70. [IF 1,9]
  • Saner FH, Treckmann JW, Geis A, Lösch C, Witzke O, Canbay A, Herget-Rosenthal S, Kribben A, Paul A, Feldkamp T. Efficacy and safety of regional citrate anticoagulation in liver transplant patients requiring post-operative renal replacement therapy. Nephrol Dial Transpl. 2011 Nov 1. [Epub ahead of print] [IF 3,6]
  • Dechêne A, El Fouly AH, Bechmann LP, Jochum C, Saner FH, Gerken G, Canbay A. Acute Management of Refractory Variceal Bleeding in Liver Cirrhosis by Self-Expanding Metal Stents. Digestion. 2012;85(3):185-191. [IF 2,1]
  • Wree A, Mayer A, Westphal S, Beilfuss A, Canbay A, Schick RR, Gerken G, Vaupel P. Adipokine Expression in Brown and White Adipocytes in Response to Hypoxia. J Endocrinol Invest. 2012;35(5):522-7. [IF 1,5]
  • Trellakis S, Rydleuskaya A, Fischer C, Canbay A, Tagay S, Scherag A, Bruderek K, Schuler J P, Brandau S. Low Adiponektin, High Levels of Apoptosis and Increased Peripheral Blood Neutrophil Acitivity in Healthy Obese Subjects. Obesity Facts. 2012;5(3):305-18. [IF 1,1]
  • Wree A, Bechmann LP, Kumarasamy N, Sommerwerck U, Jochum C, Jakob H, Baba HA, Gerken G, Kamler M, Canbay A. Elevated -glutamyltransferase is associated with mortality in lung transplantation for cystic fibrosis. Transpl Int. 2012;25(1):78-86. [IF 3,2]
  • Hadem J, Tacke F, Bruns T, Langgartner J, Strnad P, Denk GU, Fikatas P, Manns MP, Hofmann WP, Gerken G, Grünhage F, Umgelter A, Trautwein C, Canbay A, The Acute Liver Failure Study Group Germany. Etiologies and Outcomes of Acute Liver Failure in Germany. Clin Gastroenterol Hepatol. [Epub. 27 February 2012] [IF 5,3]
  • Schreiter T, Marquitan G, Darnell M, Sowa JP, Bröcker-Preuss M, Andersson TB, Baba HA, Furch M, Arteel GE, Mathé Z, Treckmann J, Gerken G, Gieseler RK, Canbay A. An ex vivo perfusion system emulating in vivo conditions in noncirrhotic and cirrhotic human liver. J Pharmacol Exp Ther. 2012;342(3):730-41. [IF 3,8]
  • Heuer M, Kaiser GM, Kahraman A, Banysch M, Saner FH, Mathé Z, Gerken G, Paul A, Canbay A, Treckmann JW. Liver transplantation in nonalcoholic steatohepatitis is associated with high mortality and post-transplant complications: a single-center experience. Digestion. 2012;86(2):107-13. [IF 2,1]
  • Gonzalez-Carmona MA, Sandhoff R, Tacke F, Vogt A, Weber S, Canbay AE, Rogler G, Sauerbruch T, Lammert F, Yildiz Y. Beta-glucosidase 2 knockout mice with increased glucosylceramide show impaired liver regeneration. Liver Int. 2012;32(9):1354-62. [IF 3,8]
  • Heuer M, Remmer N, Radünz S, Frühauf NR, Canbay A, Paul A, Kaiser GM. [Disposition for Organ Donation: Analysis of a Survey and Trial of 974 Respondents.] Zentralbl Chir. 2012 Jun 14. [Epub ahead of print] [IF 1,0]
  • Juntermanns B, Sotiropoulos GC, Radunz S, Reis H, Heuer M, Baba HA, Canbay A, Schuler M, Gerken G, Paul A, Kaiser GM. Comparison of the Sixth and the Seventh Editions of the UICC Classification for Perihilar Cholangiocarcinoma. Ann Surg Oncol. 2012 Jul 18. [Epub ahead of print] [IF 4,2]
  • Herzer K, Carbow A, Sydor S, Sowa JP, Biesterfeld S, Hofmann TG, Galle PR, Gerken G, Canbay A. Deficiency of the promyelocytic leukemia protein fosters hepatitis C-associated hepatocarcinogenesis in mice. PLoS One.2012;7(9):e44474. Epub 2012 Sep 11. [IF 4,4]
  • Sydor S, Gu Y, Schlattjan M, Bechmann LP, Rauen U, Best J, Paul A, Baba HA, Sowa JP, Gerken G, Canbay A. Steatosis does not impair liver regeneration after partial hepatectomy. Lab Invest. 2013;93(1):20-30. [IF 3,6]
  • Hinz M, Wree A, Jochum C, Bechmann LP, Saner F, Gerbes AL, Gerken G, Canbay A. High age and low sodium urine concentration are associated with poor survival in patients with hepatorenal syndrome. Ann Hepatol. 2013;12(1):92-9. [IF: 1,8]
  • Bechmann LP, Kocabayoglu P, Sowa JP, Sydor S, Best J, Schlattjan M, Beilfuss A, Schmitt J, Hannivoort RA, Kilicarslan A, Rust C, Berr F, Gerken G, Friedman SL, Geier A, Canbay A. Free fatty acids repress SHP activation and adiponectin counteracts bile acid induced liver injury in super-obese patients with NASH. Hepatology 2013;57(4):1394-406. [IF 10,9]
  • Kälsch J, Bechmann LP, Kälsch H, Kahraman A, Gerken G, Canbay A. Non-alcoholic steatohepatitis occurs in celiac disease and is associated with cellular stress. Z Gastro. 2013;51(1):26-31. [IF: 0,9]
  • Manka P, Bechmann LP, Tacke F, Sowa JP, Schlattjan M, Kälsch J, Jochum C, Paul A, Saner FH, Trautwein C, Gerken G, Canbay A. Serum sodium based modification of the MELD does not improve prediction of outcome in acute liver failure. BMC Gastroenterol. 2013;13:58. [IF 2,4]
  • Demir M, Lang S, Schlattjan M, Drebber U, Wedemeyer I, Nierhoff D, Kaul I, Sowa J, Canbay A, Töx U, Steffen HM. NIKEI: a new inexpensive and non-invasive scoring system to exclude advanced fibrosis in patients with NAFLD. PLoS One. 2013;8(3):e58360. [IF 4,4]
  • Kahraman A, Sowa JP, Schlattjan M, Sydor S, Pronadl M, Wree A, Beilfuss A, Kilicarslan A, Altınbaş A, Bechmann LP, Syn WK, Gerken G, Canbay A. Fetuin-A mRNA expression is elevated in NASH compared to NAFL patients. Clin Sci (Lond). 2013. [Epub ahead of print] [IF 4,3]
  • Fingas CD, Altinbas A, Schlattjan M, Beilfuss A, Sowa JP, Sydor S, Bechmann LP, Ertle J, Akkiz H, Herzer K, Paul A, Gerken G, Baba HA, Canbay A. Expression of Apoptosis- and Vitamin D Pathway-Related Genes in Hepatocellular Carcinoma. Digestion. 2013;87(3):176-181. [IF 2,1]
  • Sowa JP, Heider D, Bechmann LP, Gerken G, Hoffmann D, Canbay A. Novel Algorithm for Non-Invasive Assessment of Fibrosis in NAFLD. PLoS One. 2013;8(4):e62439. [IF 4,4]
  • Fingas CD, Mertens JC, Razumilava N, Sydor S, Bronk SF, Christensen JD, Rizvi SH, Canbay A, Treckmann JW, Paul A, Sirica AE, Gores GJ. Polo-like kinase 2 is a mediator of hedgehog survival signaling in cholangiocarcinoma. Hepatology. 2013 May 22. doi: 10.1002/hep.26484. [Epub ahead of print] [IF 10,9]
  • Stindt J, Ellinger P, Weissenberger K, Dröge C, Herebian D, Mayatepek E, Homey B, Braun S, Schulte am Esch J, Horacek M, Canbay A, Schmitt L, Häussinger D, Kubitz R. A novel mutation within a transmembrane helix of the bile salt export pump (BSEP, ABCB11) with delayed development of cirrhosis. Liver Int. 2013 Nov;33(10):1527-35.
  • Wree A, Eguchi A, McGeough MD, Pena CA, Johnson CD, Canbay A, Hoffman HM, Feldstein AE. NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation, and fibrosis in mice. Hepatology. 2014;59(3):898-910.
  • Landgraeber S, Putz S, Schlattjan M, Bechmann LP, Totsch M, Grabellus F, Hilken G, Jäger M, Canbay A. Adiponectin attenuates osteolysis in aseptic loosening of total hip replacements. Acta Biomater. 2014 Jan;10(1):384-93.
  • Reis H, Peterek PT, Wohlschlaeger J, Kaiser GM, Mathe Z, Juntermanns B, Sotiropoulos GC, Beckhove U, Canbay A, Wirges U, Scherag A, Treckmann JW, Paul A, Baba HA. Oil Red O-assessed macrosteatosis in liver transplant donor biopsies predicts ischemia-reperfusion injury and clinical outcome. Virchows Arch. 2014 Feb;464(2):165-74.
  • Hoyer DP, Paul A, Gallinat A, Molmenti EP, Reinhardt R, Minor T, Saner FH, Canbay A, Treckmann JW, Sotiropoulos GC, Mathé Z. Donor information based prediction of early allograft dysfunction and outcome in liver transplantation. Liver Int. 2015 Jan;35(1):156-63.
  • Saner FH, Nowak K, Hoyer D, Rath P, Canbay A, Paul A, Koldehoff M, Elmaağaclı A. A non-interventional study of the genetic polymorphisms of NOD2 associated with increased mortality in non-alcoholic liver transplant patients. BMC Gastroenterol. 2014 Jan 6;14:4.
  • Koch A, Zimmermann HW, Gassler N, Jochum C, Weiskirchen R, Bruensing J, Buendgens L, Dückers H, Bruns T, Gerken G, Neumann UP, Adams DH, Trautwein C, Canbay A, Tacke F. Clinical relevance and cellular source of elevated soluble urokinase plasminogen activator receptor (suPAR) in acute liver failure. Liver Int. 2014 Oct;34(9):1330-9.
  • Hilgard P, Dechene A, Canbay A, Herzer K, Schlaak JF, Treichel U, Gassel AM, Baba H, Zoepf T. Mini-laparoscopy is superior in detecting liver cirrhosis and metastases in liver cancer: an over 10-year experience in 1,788 cases. Digestion. 2014;89(2):156-64.
  • Hoyer DP, Munteanu M, Canbay A, Hartmann M, Gallinat A, Paul A, Saner FH. Liver transplantation for acute liver failure: are there thresholds not to be crossed? Transpl Int. 2014 Jun;27(6):625-33.
  • Reis H, Wohlschläger J, Hagemann S, Wenzel P, Bechmann LP, Suttorp AC, Schlattjan MJ, Herzer K, Canbay A, Baba HA. (Cleaved) CK18 serum and tissue expression levels differentiate acute HCV reinfection from acute rejection in liver allografts. Liver Int. 2014 Apr 22.
  • Bechmann LP, Manka P, Best J, Saner FH, Paul A, Canbay A, Gerken G. [Drug-induced liver injury as predominant cause of acute liver failure in a monocenter study]. Dtsch Med Wochenschr. 2014 May;139(17):878-82.
  • Dechêne A, Jochum C, Fingas C, Paul A, Heider D, Syn WK, Gerken G, Canbay A, Zöpf T. Endoscopic management is the treatment of choice for bile leaks after liver resection. Gastrointest Endosc. 2014;80(4):626-633.e1.
  • Wree A, McGeough MD, Peña CA, Schlattjan M, Li H, Inzaugarat ME, Messer K, Canbay A, Hoffman HM, Feldstein AE. NLRP3 inflammasome activation is required for fibrosis development in NAFLD. J Mol Med (Berl). 2014 Oct;92(10):1069-82.
  • Coombes JD, Swiderska-Syn M, Dollé L, Reid D, Eksteen B, Claridge L, Briones-Orta MA, Shetty S, Oo YH, Riva A, Chokshi S, Papa S, Mi Z, Kuo PC, Williams R, Canbay A, Adams DH, Diehl AM, van Grunsven LA, Choi SS, Syn WK. Osteopontin neutralisation abrogates the liver progenitor cell response and fibrogenesis in mice. Gut. 2014 Jun 5. pii: gutjnl-2013-306484. [Epub ahead of print]
  • Gautheron J, Vucur M, Reisinger F, Cardenas DV, Roderburg C, Koppe C, Kreggenwinkel K, Schneider AT, Bartneck M, Neumann UP, Canbay A, Reeves HL, Luedde M, Tacke F, Trautwein C, Heikenwalder M, Luedde T. A positive feedback loop between RIP3 and JNK controls non-alcoholic steatohepatitis. EMBO Mol Med. 2014 Jun 24;6(8):1062-74.
  • Sowa JP, Atmaca Ö, Kahraman A, Schlattjan M, Lindner M, Sydor S, Scherbaum N, Lackner K, Gerken G, Heider D, Arteel GE, Erim Y, Canbay A. Non-invasive separation of alcoholic and non-alcoholic liver disease with predictive modeling. PLoS One. 2014;9(7):e101444.
  • Popp W, Gantumur T, Ross B, Zorigt K, Davaadorj D, Rossburg M, Sowa JP, Canbay A. Aflatoxin exposure may not play a role in liver cancer development in mongolia. Digestion. 2014;89(4):268-71.
  • Manka P, Olliges V, Bechmann LP, Schlattjan M, Jochum C, Treckmann JW, Saner FH, Gerken G, Syn WK, Canbay A. Low levels of blood lipids are associated with etiology and lethal outcome in acute liver failure. PLoS One. 2014;9(7):e102351.
  • Padden J, Megger DA, Bracht T, Reis H, Ahrens M, Kohl M, Eisenacher M, Schlaak JF, Canbay AE, Weber F, Hoffmann AC, Kuhlmann K, Meyer HE, Baba HA, Sitek B. Identification of novel biomarker candidates for the immunohistochemical diagnosis of cholangiocellular carcinoma. Mol Cell Proteomics. 2014 Oct;13(10):2661-72.
  • Kahraman A, Wand K, Eisele L, Witzke O, Canbay A, Gerken G. [Comparison of extracorporeal liver assist devices – albumin dialysis versus plasma exchange – in acute-on-chronic liver failure]. Dtsch Med Wochenschr. 2014;139(33):1653-8.
  • Piras-Straub K, Khairzada K, Trippler M, Baba HA, Kaiser GM, Paul A, Canbay A, Weber F, Gerken G, Herzer K. TRAIL expression levels in human hepatocellular carcinoma have implications for tumor growth, recurrence and survival. Int J Cancer. 2015 Feb 15;136(4):E154-60.
  • Beilfuss A, Sowa JP, Sydor S, Beste M, Bechmann LP, Schlattjan M, Syn WK,
    Wedemeyer I, Mathé Z, Jochum C, Gerken G, Gieseler RK, Canbay A. Vitamin D counteracts fibrogenic TGF-β signalling in human hepatic stellate cells both receptor-dependently and independently. Gut. 2014 Aug 18. [Epub ahead of print]
  • Papadopoulos-Köhn A, Achterfeld A, Paul A, Canbay A, Timm J, Jochum C, Gerken G, Herzer K. Daily Low-Dose Tacrolimus Is a Safe and Effective Immunosuppressive Regimen During Telaprevir-Based Triple Therapy for Hepatitis C Virus Recurrence After Liver Transplant. Transplantation. 2014 Sep 9. [Epub ahead of print]
  • Wree A, Schlattjan M, Bechmann LP, Claudel T, Sowa JP, Stojakovic T, Scharnagl H, Köfeler H, Baba HA, Gerken G, Feldstein AE, Trauner M, Canbay A. Adipocyte cell size, free fatty acids and apolipoproteins are associated with non-alcoholic liver injury progression in severely obese patients. Metabolism. 2014 Dec;63(12):1542-52.
  • Reis H, Pütter C, Megger DA, Bracht T, Weber F, Hoffmann AC, Bertram S, Wohlschläger J, Hagemann S, Eisenacher M, Scherag A, Schlaak JF, Canbay A, Meyer HE, Sitek B, Baba HA. A structured proteomic approach identifies 14-3-3Sigma as a novel and reliable protein biomarker in panel based differential diagnostics of liver tumors. Biochim Biophys Acta. 2014 Nov 5. [Epub ahead of print]
  • Hoyer DP, Paul A, Saner F, Gallinat A, Mathé Z, Treckmann JW, Schulze M, Kaiser GM, Canbay A, Molmenti E, Sotiropoulos GC. Safely expanding the donor pool: brain dead donors with history of temporary cardiac arrest. Liver Int. 2014 Dec 19. [Epub ahead of print]
  • Dechêne A, Wree A, Maldonado EJ, Bechmann LP, Baba H, Gerken G, Syn WK, Canbay A. Mini Laparoscopy is safe in Acute Liver Failure and Reveals Liver Fibrosis as Common Feature. Digestion [accepted 11.08.2014]
  • Dechêne A, Kodde C, Kathemann S, Treckmann J, Lainka E, Paul A, Gerken G, Feldstein AE, Hoyer PF, Canbay A. Endoscopic Treatment of Pediatric post-transplant Biliary Complications is safe and effective. Digestive Endoscopy 2014 Dec 24. [Epub ahead of print]

Fallberichte

• • Rengelshausen J, Rünzi M, Canbay A, Gerken G, Philipp T. Familiäres Mittelmeerfieber: Neue Aspekte zur molekularen Genetik und Pathogenese am Beispiel dreier Kasuistiken: Med Klin 1999;94:685-9.
  • Canbay A, Peitgen K, Rünzi M. Akute Divertikulitis nach langjährig bekannter Divertikulitis. Notfallmedizin 2000;26:500-1.
  • Canbay A, Gieseler R, Ella R, Fink H, Saller B, Mann K. Manifestation einer Nebenniereninsuffizienz nach Gabe von Levothyroxin bei einem Patienten mit polyglandulärem Autoimmunsystem Typ II (Schmidt-Syndrom). Internist 2000;41:588-1.
  • Canbay A, Rünzi M, Gieseler R, Kobyletzki Gv, Alamouti D, Stücker M, Goebell H, Altmeyer P. Psoriasis pustulosa generalisata und Morbus Crohn: Neue extraintestinale Manifestation? Z Gastroenterol 2001;39:801-5.
  • Neumann T, Canbay A, Barkhausen J, Bartel T. Paracardial lipodystrophy versus effusion in HIV positive patients. Heart 2002;87:E4.
  • Canbay A, Gieseler RK, Hoffmann P, Holtmann G, Rünzi M. Persistently altered visceral perception after resection of an esophageal granular-cell myoblastoma: a therapeutic concept revisited. Z Gastroenterol 2003; 1:929-932.
  • Kahraman A, Miller M, Gieseler RK, Gerken G, Scolaro MJ, Canbay A. Non-alcoholic fatty liver disease in HIV-positive patients predisposes for acute-on-chronic liver failure: two cases. European Journal of Gastroenterology & Hepatology 2006;18:101-105.
  • Bechmann L, Best J, Jochum C, Treichel U, Gerken G, Canbay A. Crohn’s disease-induced non-alcoholic fatty liver disease (NAFLD) sensitizes for severe acute hepatitis B infection and liver failure. Z Gastroenterol. 2006; 3:245-8.
  • Gilani S, Bechmann L, Frilling A, Gerken G, Canbay A. Gallbladder endome-triosis as a cause of occult bleeding. World J Gastroenterol. 2007;13(33):4517.
  • Bechmann LP, Marquitan G, Jochum C, Saner F, Gerken G, Canbay A. Apoptosis versus necrosis rate as a predictor in acute liver failure following acetaminophen intoxication compared with acute-on-chronic liver failure. Liver Invest. 2008; 28(5):173-6
  • Katsounas A, Jochum C, Canbay A, Schlaak J, Gerlich WH, Gerken G. Core promoter mutant HBV non-responding to adefovir after viral breakthrough on lamivudine: rapid virologic response to tenofovir plus lamivudine in a cirrhotic patient. Eur J Med Res. 2008;10:472-5.
  • Dechene A, Adamzik M, Gerken G, Canbay A. Acute bronchial obstruction following esophageal stent implantation for variceal bleeding. Endoscopy 2009;41:E146-7.
  • Best J, Dechene A, Esser S, Gerken, G, Canbay A. Pregnancy-associated Sweet´s Syndrome in an Acute Episode of Ulcerative Colitis. Z Gastroenterol. 2009;47(8):753-7.
  • Kneiseler G, Bachmann HS, Bechmann LP, Dechene A, Heyer T, Baba H, Saner F, Jochum C, Gerken G, Canbay A. A rare case of propofol-induced acute liver failure and literature review. Cases in Gastroenterology 2009: In press
  • Wree A, Canbay A, Müller-Beißenhirtz H, Dechêne A, Gerken G, Dührsen U, Lammert F, Nückel H. Excessive Bilirubin Elevation in a Patient with Hereditary Spherocytosis and Intrahepatic Cholestasis. Z Gastroenterol. 2011 Aug;49(8):977-980.
  • Buechter M, Klein CG, Kloeters C, Gerken G, Canbay A, Kahraman A. Diagnostic Dilemma in a Patient with Jaundice: How to Differentiate between Autoimmune Pancreatitis, Primary Sclerosing Cholangitis and Pancreas Carcinoma. Case Rep Gastroenterol. 2012;6(1):211-6.
  • Walensi M, Canbay A, Witzke O, Gerken G, Kahraman A. Long-term therapy of a patient with summerskill-walshe-tygstrup syndrome by applying prometheus® liver dialysis: a case report. Case Rep Gastroenterol. 2012;6(2):550-6.
  • Buechter M, Klein CG, Kloeters C, Schlaak JF, Canbay A, Gerken G, Kahraman A. Tacrolimus as a reasonable alternative in a patient with steroid-dependent and thiopurine-refractory autoimmune pancreatitis with IgG4-associated cholangitis. Z Gastroenterol. 2014 Jun;52(6):564-8.

Übersichtsartikel

• • Rünzi M, Canbay A, Niebel W, Treichel U: Hämorrhoiden und Analfissuren – das verborgene Leiden. Notfallmedizin 2000; 26:502-7. [IF 0]
  • Canbay A, Treichel U, Gerken G: Liver failure – etiology and clinics. Verdauungskrankheiten 2003; 21:3-12. [IF 0]
  • Canbay A, Friedman S, Gores G. Apoptosis – the Nexus of Liver Injury and Fibrosis. Hepatology 2004: 39:273-278. [IF 10,9]
  • Canbay A, Gieseler RK, Gores GJ, Gerken G. The relationship between apoptosis and nonalcoholic fatty liver disease: an evolutionary cornerstone turned pathogenic. Z Gastroenterol 2005; 43:211-217. [IF 1,1]
  • Canbay A, Kip SN, Kahraman A, Gieseler RK, Nayci A, Gerken G. Apoptosis and fibrosis in non-alcoholic fatty liver disease. Türk. J Gastroenterol. 2005; 16:1-6. [IF 0,6]
  • Canbay A, Gerken G. Specific therapy in acute liver failure. Med Klin. 2006; 22:111-114. [IF 0,4]
  • Gerken G, Canbay A. Sterbende Leberzellen – Die Bedeutung des Zelltodes bei Lebererkrankungen. Essener Unikate Fft 27. Forschungsförderung und Transfer. Publ;2006.p. 80-87. [IF 0]
  • Canbay. A, Bechmann L, Gerken G. Lipid Metabolism in the Liver. Z Gastro-enterol. 2007;45(1):35-41. [IF 1,1]
  • Best J, Bechmann L, Gerken G, Canbay A. Rationelle Differentialdiagnostik erhöhter Leberwerte. CME Innere Medizin 2008. [IF 0]
  • Saner F, Canbay A, Gerken G, Broelsch C. Pharmacology, clinical efficiancy and safetyof terlipressin in esophageal varices bleeding, septic shock and hepatorenal syndrome. Expert Rev. Gastroenterol. Hepatol 2007;1(2):207-17. [IF 0]
  • Saner FH, Canbay A, Gerken G, Broelsch CE. Collateral damage of cephalo-sporins and quinolones and possibilities for control. Med Klin (Munich). 2009; 104(2):114-8. [IF 0]
  • Kilicarslan A, Kahraman A, Akiz H, Yildiz Menziletoglu S, Fingas CD, Gerken G, Canbay A. Apoptosis in selected liver diseases. Türk. J Gastroenterol. 2009 Sep;20(3):171-9. [IF 0,6]
  • Kahraman A, Gerken G, Canbay A. Apoptosis in immune-mediated liver disease. Digest Dis. 2010;28(1):144-9. [IF 1,0]
  • Saner FH, Akkiz H, Canbay A. Infectious complications in the early postoperative period in liver transplant patients. Minerva Gastroenterol Dietol. 2010;56(3): 355-65. [IF 0]
  • Herzer K, Post F, Canbay A, Gerken G. [Pulmonary affection in a advanced liver disease – hepatopulonary syndrome and portopulmonary hypertension]. Med Klin (Munich). 2010 Dec;105(12):916-23. [IF 0]
  • Wree A, Kahraman A, Gerken G, Canbay A. Obesity affects the liver – the link between adipocytes and hepatocytes. Digestion. 2011;83(1-2):124-33. [IF 2,1]
  • Bechmann LP, Hannivoort RA, Gerken G, Hotamisligil GS, Trauner M, Canbay A. The interaction of hepatic lipid and glucose metabolism in liver diseases. J Hepatol. 2012 Apr;56(4):952-64. [IF 9,3]
  • Canbay A, Tacke F, Hadem J, Trautwein C, Gerken G, Manns MP. Acute liver failure: a life-threatening disease. Dtsch Arztebl Int. 2011 Oct;108(42):714-20. [IF 2,1]
  • Kahraman A, Fingas CD, Syn WK, Gerken G, Canbay A. Role of stress-induced NKG2D ligands in liver disease. Liver Int. 2012 Mar;32(3):370-8. [IF 3,8]
  • V. Penndorf, F. Saner, G. Gerken, A. Canbay. Liver Parameters in Intensive Care Medicine. Zentralbl Chir. (07 Jul 2011) [IF 0,8]
  • Herzer K, Fingas CD, Canbay A. Does Ursodeoxycholic Acid Exert a Protective Effect on Liver Grafts in Orthotopic Liver Transplantation?. Digestion. 2012;86(3):206-207. [IF 2,1]
  • Kneiseler G, Canbay A, Gerken G. [Role of vitamin K antagonists from a hepatologist’s point of view]. Herz. 2012 Jun;37(4):395-401. [IF 0,92]
  • Elfimova N, Schlattjan M, Sowa JP, Dienes HP, Canbay A, Odenthal M. Circulating microRNAs: promising candidates serving as novel biomarkers of acute hepatitis. Front Physiol. 2012;3:476.
  • Wree A, Broderick L, Canbay A, Hoffman HM, Feldstein AE. From NAFLD to NASH to cirrhosis-new insights into disease mechanisms. Nat Rev Gastroenterol Hepatol. 2013 Nov;10(11):627-36.
  • Canbay A, Feldstein A, Kronenberger B, Schulze-Osthoff K, Bantel H. [Cytokeratin 18 as marker for non-invasive diagnosis and prognosis of acute and chronic liver diseases]. Z Gastroenterol. 2014 Mar;52(3):290-5.
  • Canbay AE, Glöckner A. [Liver dysfunctions in intensive care patients-consequences for the treatment of invasive Candida infections.] Med Klin Intensivmed Notfmed. 2013 Jun 26. [Epub ahead of print]
  • Saner FH, Gieseler RK, Akız H, Canbay A, Görlinger K. Delicate balance of bleeding and thrombosis in end-stage liver disease and liver transplantation. Digestion. 2013;88(3):135-44.
  • Armstrong MJ, Adams LA, Canbay A, Syn WK. Extrahepatic complications of nonalcoholic fatty liver disease. Hepatology. 2014 Mar;59(3):1174-97.

Buchkapitel

• • Canbay A, Gores G. Fas inhibition as a therapy for preventing fibrogenesis in cholestatic liver diseases. In: Galle PR, Gerken, G, Schmidt WE, editors. Disease progression and carcinogenesis in the gastrointestinal tract. Dordrecht/ Boston/ London: Kulver Acad. Publ.; 2003.
  • Canbay A, Gores G. Anti-apoptotic Intervention as a Novel Treatment Option in Liver diseases. In: Galle PR, Gerken, G, Schmidt WE, editors. Disease progression and carcinogenesis in the gastrointestinal tract. Dordrecht/ Boston/ London: Kulver Acad. Publ.; 2006.
  • Gerken G, Canbay A. Akute Virushepatitiden A und E. In: Riemann/ Fischbach/ Galle/ Mössner. In: Klinik und Praxis. Stuttgart: Thieme Verlag; 2006.
  • Canbay A, Schlaak J, Gerken G, Gieseler R; Dysregulated Apoptosis in Liver Diseases. In: Lawrence B. Schultz, editor. Cell Apoptosis: Regulation and Environmental Factors. New York: Nova Science Publishers, Inc.; 2007.
  • Kahraman, A, Gerken, Canbay A; Role of Major Histocompatibility Complex Class I-Relted Chains A and B (MIC A/B) in Liver Diseases In: Manns M, editor. Dordrecht/Boston/London: Kulver Acad. Publ.; 2010.
  • Hinz M.O., Canbay A. Das aktue Leberversagen: eine klinische und wissen-schaftliche Herausforderung. In: Eckart J, Forst H, Briegel J, editors. Intensiv-medizin. Heidelberg, München, Landsberg, Frechen, Hamburg: ecomed Medizin; September 2011.
  • Altınbaş A, Bechmann L P, Akkiz H, Gerken G, Canbay A. Acute liver failure. In: Mauss, Berg, Rockstroh, Sarrazin, Wedemeyer, (Hrsg.). Hepatology – a clinical textbook. Düsseldorf: Flying Publisher; 2012.
  • Canbay A. Nicht-alkoholische Fettlebererkrankung (NAFLD). und Akutes Leberversagen. In: Herold G und Mitarbeiter. Innere Medizin. Köln: Herold; 2012 und 2013.

Bücher

• Canbay A, Gerken G [Hrsg.]. Die Leber in der Intensivmedizin. Linkenheim-Hochstätten: Aesopus Verlag; 2010.
• Canbay A, Gerken G [Hrsg.]. Acute liver failure. Bremen-London-Boston: Uni-Med Verlag; Juni 2009.